Role of interleukin 28B rs12979860 C/T polymorphism on the histological outcome of chronic hepatitis C: relationship with gender and viral genotype.

doi:10.1007/s10875-011-9547-1

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Role of interleukin 28B rs12979860 C/T polymorphism on the histological outcome of chronic hepatitis C: relationship with gender and viral genotype.

Journal of clinical immunology - 1 Oct 2011

Falleti Edmondo, Bitetto Davide, Fabris Carlo, Cussigh Annarosa, Fornasiere Ezio, Cmet Sara, Fumolo Elisa, Bignulin Sara, Fontanini Elisabetta, Cerutti Andrea, Minisini Rosalba, Pirisi Mario, Toniutto Pierluigi

Abstract excerpt

BACKGROUND: This study aimed to determine whether the single-nucleotide polymorphism (rs12979860 C/T) of the interleukin 28B (IL-28B) gene, which is associated with hepatitis C virus (HCV) clearance, is also associated with fibrosis in chronic HCV infection. METHODS: An RFLP-PCR technique was used to genotype 629 HCV-positive patients (200 with cirrhosis) and 428 healthy control subjects. RESULTS: The genotype...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fibrosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hepacivirus

Share to Hepatitis C, Chronic

Share to Interferons

Share to Interleukins

Share to Risk

Share to Sex Factors

Share to Viral Load

Source

Open in PubMed

Identifiers

PMID: 21647799
DOI: 10.1007/s10875-011-9547-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of interleukin 28B rs12979860 C/T polymorphism on the histological outcome of chronic hepatitis C: relationship with gender and viral genotype.PMID 21647799Read ↗

IL-28B rs12979860 C/T allele distribution in patients with liver cirrhosis: role in the course of chronic viral hepatitis and the development of HCC.Semantic proximity Read ↗

IL-28B rs12979860 polymorphism affect the course of chronic hepatitis and the development of HCC in Egyptian patients with hepatitis C type 4.Semantic proximity Read ↗

The association of IL28B genotype with the histological features of chronic hepatitis C is HCV genotype dependent.Semantic proximity Read ↗

Impact of immunogenetic IL28B polymorphism on natural outcome of HCV infection.Semantic proximity Read ↗

Interleukin-28B genetic variants and hepatitis virus infection by different viral genotypes.Semantic proximity Read ↗

Impact of IL28B genetic variant's and viral genotype on treatment outcome of hepatitis C infected patients.Semantic proximity Read ↗

Interleukin-28B TT genotype is frequently found in patients with hepatitis C virus cirrhosis but does not influence hepatocarcinogenesis.Semantic proximity Read ↗

Interleukin 28B-related polymorphisms: a pathway for understanding hepatitis C virus infection?Semantic proximity Read ↗

Correlation between genetic variations and serum level of interleukin 28B with virus genotypes and disease progression in chronic hepatitis C virus infection.Semantic proximity Read ↗

Association of Interleukin 28B Polymorphism with Clearance of Hepatitis C Virus: A Mini Review.Semantic proximity Read ↗

Interleukin 28B.rs12979860 genotype does not affect hepatitis C viral load in Egyptians with genotype 4 chronic infection.Semantic proximity Read ↗

Interleukin 28B polymorphism predicts pegylated interferon plus ribavirin treatment outcome in chronic hepatitis C genotype 4.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.