IL-28B rs12979860 C/T allele distribution in patients with liver cirrhosis: role in the course of chronic viral hepatitis and the development of HCC.

doi:10.1016/j.jhep.2010.07.019

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Article

IL-28B rs12979860 C/T allele distribution in patients with liver cirrhosis: role in the course of chronic viral hepatitis and the development of HCC.

Journal of hepatology - 1 Apr 2011

Fabris Carlo, Falleti Edmondo, Cussigh Annarosa, Bitetto Davide, Fontanini Elisabetta, Bignulin Sara, Cmet Sara, Fornasiere Ezio, Fumolo Elisa, Fangazio Stefano, Cerutti Andrea, Minisini Rosalba, Pirisi Mario, Toniutto Pierluigi

Abstract excerpt

BACKGROUND & AIMS: A single nucleotide polymorphism (rs12979860 C/T) 3kb upstream of the interleukin 28B (IL-28B) gene was shown to be associated with hepatitis C clearance. We verified whether this association also translates into a different genotype distribution at the end of the disease trajectory. METHODS: A RFLP-PCR technique was used to genotype 412 patients with cirrhosis due to hepatitis C (n=199),...

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Identifiers

PMID: 21146242
DOI: 10.1016/j.jhep.2010.07.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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