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Article

microRNA-92a expression in the sera and dermal fibroblasts increases in patients with scleroderma

1 Jun 2012

Abstract excerpt

OBJECTIVES: microRNAs (miRNAs) play a part in various cellular activities. However, the role of miRNA in SSc is not fully understood. This study investigated the expression and role of miR-92a in SSc patients and evaluated the possibility that miR-92a is involved in the pathogenesis of this disease. METHODS: Serum samples were obtained from 61 SSc patients. mRNAs were purified from serum and levels of miR-92a and...

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PMID: 22661558
DOI: 10.1093/rheumatology/kes120

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