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Article

MicroRNA-29: a potential therapeutic target for systemic sclerosis

16 Jul 2012

Abstract excerpt

INTRODUCTION: Systemic sclerosis (SSc) is a systemic autoimmune disease of unknown cause characterized by microvasculopathy, fibroblast activation, and excessive production of collagen, causing tissue and organ damage. Effective medical treatment for SSc is lacking because the etiology and pathogenesis of SSc are not fully understood. MicroRNAs (miRNAs) are endogenous, regulatory, single-stranded, noncoding RNAs...

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Share to Inflammatory Myopathies and Dermatomyositis
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PMID: 22793265
DOI: 10.1517/14728222.2012.708339

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