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Article

Alteration of circulating miRNAs in SSc: miR-30b regulates the expression of PDGF receptor β

27 Jul 2013

Abstract excerpt

OBJECTIVE: Although several miRNAs have been shown to regulate autoimmune pathogenesis by affecting lymphocyte function, the roles of miRNAs in the pathogenesis of SSc remain unclear. Therefore the purpose of this study was to identify miRNAs that play a role in the pathogenesis of SSc by quantitative PCR screening of serum miRNAs. METHODS: Ninety-five miRNAs that were predicted to target SSc-related genes [IL-4,...

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Share to Inflammatory Myopathies and Dermatomyositis
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PMID: 23893664
DOI: 10.1093/rheumatology/ket254

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