Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integration of microRNA and mRNA expression profiles in the skin of systemic sclerosis patients.

Scientific reports - 17 Feb 2017

Zhou Bin, Zuo Xiao Xia, Li Yi Sha, Gao Si Ming, Dai Xiao Dan, Zhu Hong Lin, Luo Hui

Abstract excerpt

MicroRNAs (miRNAs) play important roles in the fibrosis of systemic sclerosis (SSc). However, the underlying miRNA-mRNA regulatory network is not fully understood. A systemic investigation of the role of miRNAs would be very valuable for increasing our knowledge of the pathogenesis of SSc. Here, we combined miRNA and mRNA expression profiles and bioinformatics analyses and then performed validation experiments....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Expression Profiling
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Regulatory Networks

Share to SOX2 gene

Share to Genetic Predisposition to Disease

Share to MicroRNAs

Share to RNA, Messenger

Share to Scleroderma, Systemic

Source

Open in PubMed Open full text

Identifiers

PMID: 28211533
DOI: 10.1038/srep42899
PMCID: PMC5314349

Genes

FZD2
FZD5
SOX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integration of microRNA and mRNA expression profiles in the skin of systemic sclerosis patients.PMID 28211533Read ↗

MicroRNAs: their involvement in fibrosis pathogenesis and use as diagnostic biomarkers in sclerodermaSemantic proximity Read ↗

Novel Concepts in Systemic Sclerosis Pathogenesis: Role for miRNAsSemantic proximity Read ↗

MicroRNAs in Systemic Sclerosis: Involvement in Disease Pathogenesis and Potential Use as Diagnostic Biomarkers and Therapeutic TargetsSemantic proximity Read ↗

MicroRNA-29: a potential therapeutic target for systemic sclerosisSemantic proximity Read ↗

Serum microRNA screening and functional studies reveal miR-483-5p as a potential driver of fibrosis in systemic sclerosisSemantic proximity Read ↗

Identification of lncRNA–miRNA–mRNA networks in circulating exosomes as potential biomarkers for systemic sclerosisSemantic proximity Read ↗

The Roles of Noncoding RNAs in Systemic SclerosisSemantic proximity Read ↗

Role of microRNA in the pathogenesis of systemic sclerosis tissue fibrosis and vasculopathySemantic proximity Read ↗

The role of microRNAs in autoimmune diseases with skin involvement.Semantic proximity Read ↗

The role of TGF-β or BMPR2 signaling pathway-related miRNA in pulmonary arterial hypertension and systemic sclerosisSemantic proximity Read ↗

MicroRNA-27a-3p inhibits lung and skin fibrosis of systemic sclerosis by negatively regulating SPP1Semantic proximity Read ↗

Gene Profiling in Patients with Systemic Sclerosis Reveals the Presence of Oncogenic Gene SignaturesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.