Article
Genetic polymorphisms of CYP2D6 oxidation in patients with systemic sclerosis.
European journal of clinical pharmacology - 1 Oct 2009
Skretkowicz Jadwiga, Baranska Malgorzata, Rychlik-Sych Mariola
Abstract excerpt
BACKGROUND: Involvement of genetic and environmental factors in the pathogenesis of scleroderma has contributed to a number of studies whose aim is to elucidate the way in which xenobiotics exert effects on the occurrence of autoimmune processes resulting in development of systemic sclerosis (SSc). OBJECTIVE: The study dealt with the evaluation of the genetically determined polymorphism of CYP2D6, one of the...
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