Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GLCCI1 single nucleotide polymorphisms in pediatric nephrotic syndrome.

Pediatric nephrology (Berlin, Germany) - 1 Sept 2012

Cheong Hae Il, Kang Hee Gyung, Schlondorff Johannes

Abstract excerpt

BACKGROUND: Empiric steroid therapy is the first-line therapy for pediatric nephrotic syndrome, but treatment response is variable. There are few predictors of steroid-responsiveness, although evidence for genetic factors does exist. Single nucleotide polymorphisms (SNPs) have been recently identified in the promoter region of glucocorticoid-induced transcript 1 gene (GLCCI1) which affect steroid-responsiveness...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Child, Preschool
Share to Drug Resistance

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Glucocorticoids

Share to Infant

Share to Nephrotic Syndrome

Share to Receptors, Glucocorticoid

Source

Open in PubMed Open full text

Identifiers

PMID: 22660954
DOI: 10.1007/s00467-012-2197-6
PMCID: PMC3408784

Genes

GLCCI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GLCCI1 single nucleotide polymorphisms in pediatric nephrotic syndrome.PMID 22660954Read ↗

Steroid-resistant Nephrotic Syndrome in Children: A Mini-review on Genetic Mechanisms, Predictive Biomarkers and Pharmacotherapy Strategies.Semantic proximity Read ↗

Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma.Semantic proximity Read ↗

NR3C1 variants and glucocorticoid response in childhood nephrotic syndrome in North India.Semantic proximity Read ↗

Calcineurin inhibitors in nephrotic syndrome secondary to podocyte gene mutations: a systematic review.Semantic proximity Read ↗

Pharmacology and pharmacogenetics of prednisone and prednisolone in patients with nephrotic syndromeSemantic proximity Read ↗

Genetics of childhood steroid-sensitive nephrotic syndrome.Semantic proximity Read ↗

GLCCI1 Variation Is Associated with Asthma Susceptibility and Inhaled Corticosteroid Response in a Chinese Han Population.Semantic proximity Read ↗

Association Between GLCCI1 Promoter Polymorphism (Rs37972) and Post-Transplant Hypertension in Renal Transplant Recipients.Semantic proximity Read ↗

Impact of the genetic variants of GLCCI1 on clinical features of asthmatic patients.Semantic proximity Read ↗

Association of Catalase Gene Polymorphisms with Idiopathic Nephrotic Syndrome in a Chinese Pediatric Population.Semantic proximity Read ↗

Genetic and in vivo determinants of glucocorticoid sensitivity in relation to clinical outcome of childhood nephrotic syndrome.Semantic proximity Read ↗

MDR-1 and CYP3A5 Polymorphisms in Pediatric Idiopathic Nephrotic Syndrome: Impact on Susceptibility and Response to Steroids (Preliminary Results).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.