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Article

Genetic architecture of microRNA expression and its link to complex diseases in the Japanese population.

Human molecular genetics - 4 Jun 2022

Sonehara Kyuto, Sakaue Saori, Maeda Yuichi, Hirata Jun, Kishikawa Toshihiro, Yamamoto Kenichi, Matsuoka Hidetoshi, Yoshimura Maiko, Nii Takuro, Ohshima Shiro, Kumanogoh Atsushi, Okada Yukinori

Abstract excerpt

Understanding the genetic effects on non-coding RNA (ncRNA) expression facilitates functional characterization of disease-associated genetic loci. Among several classes of ncRNAs, microRNAs (miRNAs) are key post-transcriptional gene regulators. Despite its biological importance, previous studies on the genetic architecture of miRNA expression focused mostly on the European individuals, underrepresented in other...

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Identifiers

PMID: 34919704
DOI: 10.1093/hmg/ddab361
PMCID: PMC9169454

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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