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Article

Serotonin transporter gene as a predictor of stress generation in depression.

Journal of abnormal psychology - 1 Nov 2012

Starr Lisa R, Hammen Constance, Brennan Patricia A, Najman Jake M

Abstract excerpt

Research suggests that a polymorphism in the promoter region of the serotonin transporter promoter (5-HTTLPR) interacts with stressful life events to predict depressive onset, with short (s) allele presence associated with greater susceptibility to stressors. However, this research has not considered that depressed individuals often actively generate stressful contexts. Furthermore, little is known about the...

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Identifiers

PMID: 22642841
DOI: 10.1037/a0027952
PMCID: PMC3743406

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