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Article

Life events, first depression onset and the serotonin transporter gene.

The British journal of psychiatry : the journal of mental science - 1 Mar 2006

Wilhelm Kay, Mitchell Philip B, Niven Heather, Finch Adam, Wedgwood Lucinda, Scimone Anna, Blair Ian P, Parker Gordon, Schofield Peter R

Abstract excerpt

BACKGROUND: A relationship between the serotonin transporter gene, adverse events and onset of major depression has been reported. AIMS: To replicate a gene x environment interaction in a cohort with longitudinal data for life events, experience of depression, parental bonding and neuroticism. METHOD: At the 25-year follow-up, genomic DNA was obtained from 127 cohort members (mean age 48 years) to determine the...

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Identifiers

PMID: 16507960
DOI: 10.1192/bjp.bp.105.009522

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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