Article
Chronic and acute stress, gender, and serotonin transporter gene-environment interactions predicting depression symptoms in youth.
Journal of child psychology and psychiatry, and allied disciplines - 1 Feb 2010
Hammen Constance, Brennan Patricia A, Keenan-Miller Danielle, Hazel Nicholas A, Najman Jake M
Abstract excerpt
BACKGROUND: Many recent studies of serotonin transporter gene by environment effects predicting depression have used stress assessments with undefined or poor psychometric methods, possibly contributing to wide variation in findings. The present study attempted to distinguish between effects of acute and chronic stress to predict depressive symptoms at age 20 among 346 youth varying in polymorphisms of the 5HTT...
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