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Article

The hypoxic microenvironment upgrades stem-like properties of ovarian cancer cells.

BMC cancer - 29 May 2012

Liang Dongming, Ma Yuanyuan, Liu Jian, Trope Claes Goran, Holm Ruth, Nesland Jahn M, Suo Zhenhe

Abstract excerpt

BACKGROUND: To study whether hypoxia influences the stem-like properties of ovarian cancer cells and their biological behavior under hypoxia. METHOD: Ovarian cancer cell lines ES-2 and OVCAR-3 were cultivated in different oxygen tensions for proliferation, cell cycling and invasion analyses. The...

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Identifiers

PMID: 22642602
DOI: 10.1186/1471-2407-12-201
PMCID: PMC3407800

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22642602-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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