Article
Ovarian cancer stem cells are enriched in side population and aldehyde dehydrogenase bright overlapping population.
PloS one - 1 Jan 2013
Yasuda Kazuyo, Torigoe Toshihiko, Morita Rena, Kuroda Takahumi, Takahashi Akari, Matsuzaki Junichi, Kochin Vitaly, Asanuma Hiroko, Hasegawa Tadashi, Saito Tsuyoshi, Hirohashi Yoshihiko, Sato Noriyuki
Abstract excerpt
Cancer stem-like cells (CSCs)/cancer-initiaiting cells (CICs) are defined as a small population of cancer cells that have self-renewal capacity, differentiation potential and high tumor-initiating ability. CSCs/CICs of ovarian cancer have been isolated by side population (SP) analysis, ALDEFLUOR assay and using cell surface markers. However, these approaches are not definitive markers for CSCs/CICs, and it is...
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