Article
Predicting inhaled corticosteroid response in asthma with two associated SNPs.
The pharmacogenomics journal - 1 Aug 2013
McGeachie M J, Wu A C, Chang H-H, Lima J J, Peters S P, Tantisira K G
Abstract excerpt
Inhaled corticosteroids (ICS) are the most commonly used controller medications prescribed for asthma. Two single-nucleotide polymorphisms (SNPs), rs1876828 in corticotrophin releasing hormone receptor 1 and rs37973 in GLCCI1, have previously been associated with corticosteroid efficacy. We studied data from four existing clinical trials of asthmatics, who received ICS and had lung function measured by forced...
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