Article
Bioconjugation of green fluorescent protein via an unexpectedly stable cyclic sulfonium intermediate.
Chembiochem : a European journal of chemical biology - 18 Jun 2012
Nathani Ramiz, Moody Paul, Smith Mark E B, Fitzmaurice Richard J, Caddick Stephen
Abstract excerpt
Smooth converter: Bioconjugation of superfolder GFP involving the formation of an unusually stable, and unprecedented, cyclic sulfonium species is described. This sulfonium can undergo smooth reaction with a range of nucleophiles to give sulfur-, selenium- and azide-modified GFP derivatives in high conversions.
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