Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

COUP-TF gene: a structure unique for the steroid/thyroid receptor superfamily.

Nucleic acids research - 11 Dec 1990

Ritchie H H, Wang L H, Tsai S, O'Malley B W, Tsai M J

Abstract excerpt

Two different genomic genes for the COUP-transcription factor, COUP-TF I and COUP-TF II, have been isolated from a human cosmid genomic library using a [32P]-labeled cDNA probe. Data obtained from Southern blot analysis of these cosmid clones indicated that two closely related genes exist in the human genome and have a similar genomic organization. The genes are similar in the hormone and DNA binding domains but...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Blotting, Southern
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Genetic Variation

Share to Molecular Sequence Data

Share to Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 2263450
DOI: 10.1093/nar/18.23.6857
PMCID: PMC332742

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

COUP-TF gene: a structure unique for the steroid/thyroid receptor superfamily.PMID 2263450Read ↗

Deletion of the orphan nuclear receptor COUP-TFII in uterus leads to placental deficiencySemantic proximity Read ↗

COUP-TFII Regulates Human Endometrial Stromal Genes Involved in InflammationSemantic proximity Read ↗

Identification of COUP-TFII Orphan Nuclear Receptor as a Retinoic Acid–Activated ReceptorSemantic proximity Read ↗

Chicken Ovalbumin Upstream Promoter Transcription Factor (COUP-TF) Dimers Bind to Different GGTCA Response Elements, Allowing COUP-TF To Repress Hormonal Induction of the Vitamin D<sub>3</sub>, Thyroid Hormone, and Retinoic Acid ReceptorsSemantic proximity Read ↗

The COUP-TFII variant lacking a DNA-binding domain inhibits the activation of the Cyp7a1 promoter through physical interaction with COUP-TFII.Semantic proximity Read ↗

Evidence for NR2F2/COUP-TFII involvement in human testis development.Semantic proximity Read ↗

Molecular mechanism of chicken ovalbumin upstream promoter-transcription factor (COUP-TF) actionsSemantic proximity Read ↗

Dynamic expression of COUP-TFI and COUP-TFII during development and functional maturation of the mouse inner ear.Semantic proximity Read ↗

Characterization of the mouse FTZ-F1 gene, which encodes a key regulator of steroid hydroxylase gene expression.Semantic proximity Read ↗

Identification of a regulatory function for an orphan receptor in muscle: COUP-TF II affects the expression of the myoD gene family during myogenesis.Semantic proximity Read ↗

De novo frameshift mutation in COUP-TFII (NR2F2) in human congenital diaphragmatic hernia.Semantic proximity Read ↗

The Chicken Ovalbumin Upstream Promoter-Transcription Factor II Negatively Regulates the Transactivation of Androgen Receptor in Prostate Cancer CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.