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Article

COUP-TFII Regulates Human Endometrial Stromal Genes Involved in Inflammation

1 Nov 2013

Abstract excerpt

Chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII; NR2F2) is an orphan nuclear receptor involved in cell-fate specification, organogenesis, angiogenesis, and metabolism. Ablation of COUP-TFII in the mouse uterus causes infertility due to defects in embryo attachment and impaired uterine stromal cell decidualization. Although the function of COUP-TFII in uterine decidualization has been...

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PMID: 24176914
DOI: 10.1210/me.2013-1191

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COUP-TFII Regulates Human Endometrial Stromal Genes Involved in InflammationPMID 24176914Read ↗

COUP-TFII Mediates Progesterone Regulation of Uterine Implantation by Controlling ER ActivitySemantic proximity Read ↗

Deletion of the orphan nuclear receptor COUP-TFII in uterus leads to placental deficiencySemantic proximity Read ↗

The NR2F2-HAND2 signaling axis regulates progesterone actions in the uterus at early pregnancySemantic proximity Read ↗

Identification of COUP-TFII Orphan Nuclear Receptor as a Retinoic Acid–Activated ReceptorSemantic proximity Read ↗

Genome-Wide DNA Methylation Analysis Predicts an Epigenetic Switch for GATA Factor Expression in EndometriosisSemantic proximity Read ↗

Chicken ovalbumin upstream promoter transcription factor type II interacts and functionally cooperates with GATA4 to regulate anti‐Müllerian hormone receptor type 2 transcription in mouse MA‐10 Leydig cellsSemantic proximity Read ↗

Generation of heterozygous (MCRIi030-A-1) and homozygous (MCRIi030-A-2) NR2F2/COUP-TFII knockout human iPSC lines.Semantic proximity Read ↗

Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatmentSemantic proximity Read ↗

Evidence for <i>NR2F2</i> /COUP-TFII involvement in human testis developmentSemantic proximity Read ↗

Loss of Function of the Nuclear Receptor NR2F2, Encoding COUP-TF2, Causes Testis Development and Cardiac Defects in 46,XX Children.Semantic proximity Read ↗

Evidence for NR2F2/COUP-TFII involvement in human testis development.Semantic proximity Read ↗

Integrated chromatin immunoprecipitation sequencing and microarray analysis identifies FOXA2 target genes in the glands of the mouse uterusSemantic proximity Read ↗

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