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Article

Association of the IL28B genotype with insulin resistance in patients with chronic hepatitis C.

Journal of hepatology - 1 Sept 2012

Stättermayer Albert Friedrich, Rutter Karoline, Beinhardt Sandra, Scherzer Thomas-Matthias, Stadlmayr Andreas, Hofer Harald, Wrba Fritz, Steindl-Munda Petra, Krebs Michael, Datz Christian, Trauner Michael, Ferenci Peter

Abstract excerpt

BACKGROUND & AIMS: Insulin resistance, fibrosis and steatosis are established predictors of response to peg-interferon/ribavirin therapy in chronic hepatitis C (CHC). Several host genetic polymorphisms (IL28B, PNPLA3) modify treatment-outcome, the degree of steatosis or fibrosis. The aim of our study was to evaluate the role of these polymorphisms on insulin resistance (IR) in treatment-naïve patients with...

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Source

Identifiers

PMID: 22634340
DOI: 10.1016/j.jhep.2012.04.036

Genes

PNPLA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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