Article
Interleukin 28B genotype and insulin resistance in chronic hepatitis C patients.
Antiviral therapy - 1 Jan 2014
Degasperi Elisabetta, Valenti Luca, Aghemo Alessio, De Francesco Raffaele, Rumi Mariagrazia, Soffredini Roberta, Donnici Lorena, Cheroni Cristina, Fargion Silvia, Zanoni Valeria, Orsi Emanuela, Colombo Massimo
Abstract excerpt
BACKGROUND: In patients with chronic HCV infection, an association between IL28B genotype and insulin-resistance (IR), known predictors of sustained virological response (SVR) to pegylated interferon (PEG-IFN) and ribavirin (RBV) therapy, has been reported. The aim of this study was to investigate the association of IR and IL28B genotype in two cohorts of well-characterized HCV patients. METHODS: A total of 480...
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