Article
Insulin resistance in chronic hepatitis C: association with genotypes 1 and 4, serum HCV RNA level, and liver fibrosis.
Gastroenterology - 1 Feb 2008
Moucari Rami, Asselah Tarik, Cazals-Hatem Dominique, Voitot Hélène, Boyer Nathalie, Ripault Marie-Pierre, Sobesky Rodolphe, Martinot-Peignoux Michèle, Maylin Sarah, Nicolas-Chanoine Marie-Hélène, Paradis Valérie, Vidaud Michel, Valla Dominique, Bedossa Pierre, Marcellin Patrick
Abstract excerpt
BACKGROUND & AIMS: Our study was designed to test the association between insulin resistance (IR) and hepatitis C virus (HCV) genotypes, serum HCV RNA level and liver fibrosis stage in a large prospective cohort of chronic hepatitis C (CHC) patients. METHODS: Six hundred consecutive patients (CHC, n = 500; chronic hepatitis B (CHB), n = 100) were evaluated on the day of liver biopsy. IR (Homeostasis Model for...
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