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Article

Insulin resistance is independently associated with significant hepatic fibrosis in Asian chronic hepatitis C genotype 2 or 3 patients.

Journal of gastroenterology and hepatology - 1 Jul 2011

Patel Keyur, Thompson Alexander J, Chuang Wan-Long, Lee Chuan-Mo, Peng Chen-Yuan, Shanmuganathan Ganesananthan, Thongsawat Satawat, Tanwandee Tawesak, Mahachai Varocha, Pramoolsinsap Chutima, Cho Mong, Han Kwang Hyup, Shah Samir R, Foster Graham R, Clark Paul J, Pulkstenis Erik, Subramanian G Mani, McHutchison John G

Abstract excerpt

BACKGROUND AND AIM: The role of insulin resistance (IR) and hepatic steatosis in fibrogenesis in chronic hepatitis C infection (CHC) has yielded conflicting data and few studies have been performed in Asian-region populations. We retrospectively investigated the relationship between host metabolic variables, including IR and hepatic steatosis, to hepatic fibrosis in Asian-region CHC genotype 2/3 patients....

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PMID: 21410752
DOI: 10.1111/j.1440-1746.2011.06722.x

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