Article
Genetic Variants in Interleukin-28B Are Associated with Diabetes and Diabetes-Related Complications in Patients with Chronic Hepatitis C Virus Infection.
Digestive diseases and sciences - 1 Jul 2015
Kanwal Fasiha, White Donna L, Jiao Li, Tavakoli-Tabasi Shahriar, Sansgiry Shubhada, Ramsey David J, Kuzniarek Jill, Spiegelman Andrew, El-Serag Hashem B
Abstract excerpt
BACKGROUND: Few studies have shown that host interleukin-28B (IL28B) genetic polymorphisms are associated with insulin resistance in patients with chronic hepatitis C virus (HCV) infection. However, the clinical relevance of this relationship is unclear. AIMS: We examined the association between IL28B genotype for rs12980275 and risk of type 2 diabetes and diabetes-related complications. METHODS: We used a...
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