Article
Comparing HLA shared epitopes in French Caucasian patients with scleroderma.
PloS one - 1 Jan 2012
Azzouz Doua F, Rak Justyna M, Fajardy Isabelle, Allanore Yannick, Tiev Kiet Phong, Farge-Bancel Dominique, Martin Marielle, Kanaan Sami B, Pagni Philippe P, Hachulla Eric, Harlé Jean Robert, Didelot Rémi, Granel Brigitte, Cabane Jean, Roudier Jean, Lambert Nathalie C
Abstract excerpt
Although many studies have analyzed HLA allele frequencies in several ethnic groups in patients with scleroderma (SSc), none has been done in French Caucasian patients and none has evaluated which one of the common amino acid sequences, (67)FLEDR(71), shared by HLA-DRB susceptibility alleles, or (71)TRAELDT(77), shared by HLA-DQB1 susceptibility alleles in SSc, was the most important to develop the disease....
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