Article
Association of the HLA-DRB1 with scleroderma in Chinese population.
PloS one - 1 Jan 2014
He Dongyi, Wang Jiucun, Yi Lin, Guo Xinjian, Guo Shicheng, Guo Gang, Tu Wenzhen, Wu Wenyu, Yang Li, Xiao Rong, Li Yuan, Chu Haiyan, Lai Syeling, Jin Li, Zou Hejian, Reveille John D, Assassi Shervin, Mayes Maureen D, Zhou Xiaodong
Abstract excerpt
Multiple alleles of the Human leukocyte antigen (HLA) DRB1 have been strongly associated with systemic sclerosis (SSc) and its clinical or serological subsets. However, the associations vary in different ethnic populations. To define SSc-risk and/or -protective alleles of HLA-DRB1 in Chinese population, we studied a Han Chinese cohort containing 585 patients with SSc and 458 gender-matched, unrelated controls....
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