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Article

Transforming growth factor beta1 gene variation Leu10Pro affects secretion and function in hepatic cells.

Digestive diseases and sciences - 1 Nov 2012

Gu Xing, Ji Xin, Shi Le-Hua, Yi Chang-Hong, Zhao Yun-Peng, Wang Ai-Hua, Lu Lun-Gen, Yu Wen-Bo, Gao Chun-Fang

Abstract excerpt

BACKGROUND: Our previous work revealed transforming growth factor beta1 (TGFβ1) gene polymorphisms are associated with susceptibility to hepatocellular carcinoma and liver cirrhosis. However, no further study of functional substitution in hepatic cells has yet been reported. AIMS: This study was designed to uncover the functional mechanisms of TGFβ1 gene polymorphisms in the pathogenesis of liver diseases....

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PMID: 22615019
DOI: 10.1007/s10620-012-2238-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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