Article
Transforming growth factor beta 1 gene variants increase transcription and are associated with liver cirrhosis in Chinese.
Cytokine - 1 Jul 2008
Wang Hao, Zhao Yun-Peng, Gao Chun-Fang, Ji Qiang, Gressner Axel M, Yang Zai-Xing, Weiskirchen Ralf
Abstract excerpt
BACKGROUND AND AIMS: Transforming growth factor beta1 (TGFbeta1) acts as an important profibrogenic cytokine in liver fibrogenesis. The aim of this study was to explore the association between TGFbeta1 gene polymorphisms and liver cirrhosis. METHODS: Totally 118 Chinese suffering from liver cirrhosis induced by HBV infection and 104 healthy controls were recruited. The polymorphisms at positions -988, -800, -509...
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