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Article

Influence of transforming growth factor-beta1 gene polymorphism at codon 10 on the development of cirrhosis in chronic hepatitis B virus carriers.

Journal of Korean medical science - 1 Apr 2010

Yu Sang Kyun, Kwon Oh Sang, Jung Hyuk Sang, Bae Kyung Suk, Kwon Kwang An, Kim Yu Kyung, Kim Yun Soo, Kim Ju Hyun

Abstract excerpt

Transforming growth factor (TGF)-beta1 is a key cytokine producing extracellular matrix. We evaluated the effect of TGF-beta1 gene polymorphism at codon 10 on the development of cirrhosis in patients with chronic hepatitis B. One hundred seventy eight patients with chronic hepatitis (CH, n=57) or liver cirrhosis (LC, n=121), who had HBsAg and were over 50 yr old, were enrolled. The genotypes were determined by...

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Identifiers

PMID: 20357999
DOI: 10.3346/jkms.2010.25.4.564
PMCID: PMC2844609

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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