Article
Functional promoter rs2868371 variant of HSPB1 associates with radiation-induced esophageal toxicity in patients with non-small-cell lung cancer treated with radio(chemo)therapy.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Nov 2011
Lopez Guerra Jose Luis, Wei Qingyi, Yuan Xianglin, Gomez Daniel, Liu Zhensheng, Zhuang Yan, Yin Ming, Li Minghuan, Wang Li-E, Cox James D, Liao Zhongxing
Abstract excerpt
PURPOSE: We investigated the association between single-nucleotide polymorphisms (SNPs) in the heat shock protein beta-1 (HSPB1) gene and the risk of radiation-induced esophageal toxicity (RIET) in patients with non-small-cell lung cancer (NSCLC). MATERIALS AND METHODS: The experimental dataset comprised 120 NSCLC patients who were treated with radio(chemo)therapy between 2005 and 2009, when novel radiation...
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