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Article

Variations in HSPA1B at 6p21.3 are associated with lung cancer risk and prognosis in Chinese populations.

Cancer research - 15 Dec 2011

Guo Huan, Deng Qifei, Wu Chen, Hu Lingmin, Wei Sheng, Xu Ping, Kuang Dan, Liu Li, Hu Zhibin, Miao Xiaoping, Shen Hongbing, Lin Dongxin, Wu Tangchun

Abstract excerpt

The heat shock protein Hsp70 is crucial for regulating cellular homeostasis in stressed cells. Although the tumorigenic potential and prognostic applications of Hsp70 have been widely investigated, it remains unclear whether genetic variations of the human isoforms HSPA1L, HSPA1A, and HSPA1B are associated with cancer risk and prognosis. In this study, we genotyped six tagSNPs in these genes in 1,152 paired...

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PMID: 22037874
DOI: 10.1158/0008-5472.CAN-11-1409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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