Article
Risk in complex genetics: "all models are wrong but some are useful".
Annals of neurology - 1 Oct 2012
Sawcer Stephen, Wason James
Abstract excerpt
Although genome-wide association studies (GWAS) have proven remarkably effective at identifying reliably associated genetic variants, the biology underlying these discoveries is rarely immediately apparent and in most cases seems bound to require extensive fine mapping and functional analysis before it is revealed. In this context, it is logical and appropriate to try to interrogate available genetic data for...
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