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Article

Apolipoprotein E genotype: the innocent bystander or active bridge between metabolic syndrome and cognitive impairment?

Journal of Alzheimer's disease : JAD - 1 Jan 2012

Frisardi Vincenza

Abstract excerpt

Apolipoprotein E [ApoE, APOE (gene)] is a multifunctional protein of the lipid and lipoprotein transport system mainly involved in metabolism of dietary lipids. Its polymorphic variants are considered a genetic risk factor of cognitive impairment in several neurodegenerative disorders such as Lewy body dementia, Huntington's disease, and Alzheimer's disease, as well as in vascular dementia and cerebrovascular...

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Source

Identifiers

PMID: 22596266
DOI: 10.3233/JAD-2012-111568

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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