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Article

Factors Influencing Alzheimer's Disease Risk: Whether and How They are Related to the APOE Genotype.

Neuroscience bulletin - 1 Jul 2022

Zhang Rong, Xu Xiaojiao, Yu Hang, Xu Xiaolan, Wang Manli, Le Weidong

Abstract excerpt

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease featuring progressive cognitive impairment. Although the etiology of late-onset AD remains unclear, the close association of AD with apolipoprotein E (APOE), a gene that mainly regulates lipid metabolism, has been firmly established and may shed light on the exploration of AD pathogenesis and therapy. However, various confounding factors...

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Identifiers

PMID: 35149974
DOI: 10.1007/s12264-021-00814-5
PMCID: PMC9276873

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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