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The human hepatocyte cell lines IHH and HepaRG: models to study glucose, lipid and lipoprotein metabolism

18 May 2012

Abstract excerpt

Metabolic diseases reach epidemic proportions. A better knowledge of the associated alterations in the metabolic pathways in the liver is necessary. These studies need in vitro human cell models. Several human hepatoma models are used, but the response of many metabolic pathways to physiological stimuli is often lost. Here, we characterize two human hepatocyte cell lines, IHH and HepaRG, by analysing the...

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PMID: 22594799
DOI: 10.3109/13813455.2012.683442

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