Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prominent Steatosis with Hypermetabolism of the Cell Line Permissive for Years of Infection with Hepatitis C Virus

9 Apr 2014

Abstract excerpt

Most of experiments for HCV infection have been done using lytic infection systems, in which HCV-infected cells inevitably die. Here, to elucidate metabolic alteration in HCV-infected cells in a more stable condition, we established an HCV-persistently-infected cell line, designated as HPI cells. This cell line has displayed prominent steatosis and supported HCV infection for more than 2 years, which is the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genomics, phytochemicals, and oxidative stress
Share to Hepatitis C virus research
Share to Liver Disease Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24718268
DOI: 10.1371/journal.pone.0094460

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prominent Steatosis with Hypermetabolism of the Cell Line Permissive for Years of Infection with Hepatitis C VirusPMID 24718268Read ↗

A broad investigation of the HBV-mediated changes to primary hepatocyte physiology reveals HBV significantly alters metabolic pathwaysSemantic proximity Read ↗

Hepatitis B Virus Associated Hepatocarcinoma Activated Unique Metabolism Pathway to Gain Survival AdvantagesSemantic proximity Read ↗

Metabolomics and Lipidomics Screening Reveal Reprogrammed Signaling Pathways toward Cancer Development in Non-Alcoholic SteatohepatitisSemantic proximity Read ↗

Hepatitis C Virus Remodels Lipid Droplets to Promote Mitochondrial Fatty Acid Accumulation and Metabolic ActivationSemantic proximity Read ↗

Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumoursSemantic proximity Read ↗

Human Hepatic Cell line 5 : In-Vitro Model for Hepatic ImmunobiologySemantic proximity Read ↗

Reliance of Host Cholesterol Metabolic Pathways for the Life Cycle of Hepatitis C VirusSemantic proximity Read ↗

PEMT Mediates Hepatitis C Virus-Induced Steatosis, Explains Genotype-Specific Phenotypes and Supports Virus Replication.Semantic proximity Read ↗

Combined Analysis of Metabolomes, Proteomes, and Transcriptomes of Hepatitis C Virus–Infected Cells and Liver to Identify Pathways Associated With Disease DevelopmentSemantic proximity Read ↗

PBMC transcriptomics identifies immune-metabolism disorder during the development of HBV-ACLFSemantic proximity Read ↗

Characterization of diseased primary human hepatocytes in an all-human cell-based triculture systemSemantic proximity Read ↗

Modulation of host lipid metabolism by hepatitis C virus: Role of new therapies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.