Article
Prognostic importance of VEGF-A haplotype combinations in a stage II colon cancer population.
Pharmacogenomics - 1 May 2012
Kjaer-Frifeldt Sanne, Fredslund Rikke, Lindebjerg Jan, Hansen Torben Froestrup, Spindler Karen-Lise Garm, Jakobsen Anders
Abstract excerpt
AIM: To investigate the prognostic effect of three VEGF-A SNPs, -2578, -460 and 405, as well as the corresponding haplotype combinations, in a unique population of stage II colon cancer patients. PATIENTS & METHODS: The study included all patients diagnosed with stage II colon cancer in Denmark in 2003 (698 patients). One paraffin-embedded tissue block from each patient was used for DNA extraction and analysis of...
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