Article
Investigation of Vascular Endothelial Growth Factor Polymorphisms on Risk, Metastasis, Laterality, and Prognosis of Colorectal Cancer in Turkish Subjects.
Genetic testing and molecular biomarkers - 1 May 2022
Cevik Mehtap, Namal Esat, Dinc-Sener Nur, Iner-Koksal Ulkuhan, Ciftci Cavlan, Susleyici Belgin
Abstract excerpt
Objectives: Tumor angiogenesis is known to support the spread and invasion of tumor cells, allow distant organ metastasis and to result in poorer prognoses and increased mortality. Since vascular endothelial growth factor-A (VEGF-A) is the major regulator of angiogenesis, in the present study the...
Topics
- Case-Control Studies
- Colorectal Neoplasms
- Genetic Predisposition to Disease
- Genotype
- Humans
- Neoplasm Metastasis
- Neovascularization, Pathologic
- Polymorphism, Single Nucleotide
- Turkey
- Vascular Endothelial Growth Factor A