Article
VEGF gene polymorphisms and outcome of epithelial ovarian cancer patients.
Future oncology (London, England) - 1 Feb 2017
Camerin Gabriela Ribeiro, Brito Angelo Borsarelli Carvalho, Vassallo José, Derchain Sophie Françoise Mauricette, Lima Carmen Silvia Passos
Abstract excerpt
AIM: Since VEGF polymorphisms were associated with variable protein production, we analyzed herein their roles in outcome of epithelial ovarian cancer (EOC) patients. METHODS: Genotypes of 85 patients with primary EOC were identified in DNA by real-time PCR. Progression-free survival and overall survival were analyzed using Kaplan-Meier method, univariate Cox model and bootstrap resampling study. RESULTS: At 60...
Topics
- Alleles
- Antineoplastic Combined Chemotherapy Protocols
- Carcinoma, Ovarian Epithelial
- Female
- Follow-Up Studies
- Genotype
- Humans
- Kaplan-Meier Estimate
- Linkage Disequilibrium
- Neoplasm Staging
- Neoplasms, Glandular and Epithelial
- Ovarian Neoplasms
- Patient Outcome Assessment
- Polymorphism, Single Nucleotide
- Prognosis
- Vascular Endothelial Growth Factor A