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Article

Genetic polymorphism in a VEGF-independent angiogenesis gene ANGPT1 and overall survival of colorectal cancer patients after surgical resection.

PloS one - 1 Jan 2012

Dai Jingyao, Wan Shaogui, Zhou Feng, Myers Ronald E, Guo Xu, Li Bingshan, Fu Xiaoying, Palazzo Juan P, Dou Kefeng, Yang Hushan, Xing Jinliang

Abstract excerpt

BACKGROUND: The VEGF-independent angiogenic signaling plays an important role in the development of colorectal cancer (CRC). However, its implication in the clinical outcome of CRC has not been reported. This study aimed to investigate the association between genetic variations in several major VEGF-independent signaling pathway genes and the overall survival of CRC patients. METHODS: Seven single nucleotide...

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Source

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Identifiers

PMID: 22496856
DOI: 10.1371/journal.pone.0034758
PMCID: PMC3319640

Genes

ANGPT1
AMOT
DLL4
ENG

Provenance

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