Article
Correlating rrs and eis promoter mutations in clinical isolates of Mycobacterium tuberculosis with phenotypic susceptibility levels to the second-line injectables.
International journal of mycobacteriology - 1 Mar 2016
Kambli Priti, Ajbani Kanchan, Nikam Chaitali, Sadani Meeta, Shetty Anjali, Udwadia Zarir, Georghiou Sophia B, Rodwell Timothy C, Catanzaro Antonino, Rodrigues Camilla
Abstract excerpt
OBJECTIVE/BACKGROUND: The in vitro drug-susceptibility testing of Mycobacterium tuberculosis reports isolates as resistant or susceptible on the basis of single critical concentrations. It is evident that drug resistance in M. tuberculosis is quite heterogeneous, and involves low level, moderate level, and high level of drug-resistant phenotypes. Thus, the aim of our study was to correlate rrs (X52917) and eis...
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