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Article

The obesity-related polymorphism PCSK1 rs6235 is associated with essential hypertension in the Han Chinese population.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 Oct 2012

Li Xiao-Mu, Ling Yan, Lu Da-Ru, Lu Zhi-Qiang, Liu Ying, Chen Hong-Yan, Gao Xin

Abstract excerpt

Proprotein convertase subtilisin/kexin-type 1 (PCSK1) is a prohormone convertase that has an important role in prohormone maturation including the process of prorenin to renin. We studied the association of the PCSK1 single-nucleotide polymorphism (SNP) rs6235 (encoding an S690T substitution) with essential hypertension (EH), obesity and related traits in the Han Chinese population. The rs6235 SNP in the PCSK1...

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Source

Identifiers

PMID: 22592666
DOI: 10.1038/hr.2012.79

Genes

PCSK1

Variants

rs6235

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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