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Article

Effect of IL12A and IL12B polymorphisms on the risk of Chlamydia trachomatis-induced tubal factor infertility and disease severity.

Human reproduction (Oxford, England) - 1 Jul 2012

Ohman H, Bailey R, Natividad A, Ragoussis J, Johnson L-L, Tiitinen A, Halttunen M, Paavonen J, Surcel H-M

Abstract excerpt

BACKGROUND: Interleukin-12 (IL-12) and related cytokines induce activation and differentiation of T cells. Our aim was to investigate the associations between genetic differences in IL-12-family cytokines and the pathogenesis of chlamydial disease. METHODS: The final study population consisted of 100 women with Chlamydia trachomatis-induced tubal factor infertility (TFI) and 125 pregnant women as controls. Three...

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Identifiers

PMID: 22581790
DOI: 10.1093/humrep/des136
PMCID: PMC3376158

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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