Article
Association between IL12B polymorphisms and tuberculosis risk: a meta-analysis.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jan 2014
Liu Guoyuan, Li Guanghua, Xu Ying, Song Na, Shen Suqin, Jiang Deke, Zeng Wenjiao, Wang Honghai
Abstract excerpt
The interleukin (IL) 12B gene encodes p40, the subunit of both IL-12 and IL-23, which are important regulators of the type I T helper cell (TH1) immune response. IL12B 3' UTR and promoter polymorphisms have been reported to be correlated with IL-12 p40 production and have been suggested to be associated with TB (tuberculosis) susceptibility. Studies that have investigated the associations between these...
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