Article
Immunogenetic correlates for Chlamydia trachomatis-associated tubal infertility.
Obstetrics and gynecology - 1 Mar 2003
Cohen Craig R, Gichui Joseph, Rukaria Rachel, Sinei Samuel S, Gaur Lakshmi K, Brunham Robert C
Abstract excerpt
OBJECTIVE: To understand immunogenetic mechanisms of Chlamydia trachomatis infection and tubal scarring. METHODS: We measured and compared previously significant human leukocyte antigen (HLA) class II DQ alleles, their linked DRB genes, and polymorphisms in selected cytokine genes (tumor necrosis factor alpha-308 promoter; transforming growth factor beta1-10 and -25 codons; interleukin 10-1082, -819, and -592...
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