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Article

Gene Polymorphisms of TLR4 and TLR9 and Haemophilus influenzae Meningitis in Angolan Children.

Genes - 21 Sept 2020

Tenhu Elina, Teräsjärvi Johanna, Cruzeiro Manuel Leite, Savonius Okko, Rugemalira Emilie, Roine Irmeli, He Qiushui, Pelkonen Tuula

Abstract excerpt

Bacterial meningitis (BM) is a severe disease caused by various bacterial pathogens. Toll-like receptors (TLRs) protect humans from invading pathogens. In this study, we determined whether single nucleotide polymorphisms (SNPs) of TLR4 and TLR9 are associated with susceptibility to and outcome of BM in Angolan children. Samples were taken from 241 patients and 265 age-matched ethnic controls. The SNPs TLR4...

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Haemophilus Infections
Haemophilus influenzae
Infant
Infant, Newborn
Neisseria meningitidis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Streptococcus pneumoniae

Toll-Like Receptor 4

Toll-Like Receptor 9

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Identifiers

PMID: 32967147
DOI: 10.3390/genes11091099
PMCID: PMC7564843

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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