Article
CD14 C-159T and toll-like receptor 4 Asp299Gly polymorphisms in surviving meningococcal disease patients.
PloS one - 7 Oct 2009
Biebl Ariane, Muendlein Axel, Kazakbaeva Zhyrgal, Heuberger Sigrid, Sonderegger Gudrun, Drexel Heinz, Lau Susanne, Nickel Renate, Kabesch Michael, Simma Burkhard
Abstract excerpt
BACKGROUND: Carriage of Neisseria meningitidis occurs approximately in 10% of the population, onset of invasive meningococcal disease (IMD) cannot be predicted and differs between ages. It remains unclear, which host factors determine invasion of the bloodstream by the bacteria. Innate immunity h...
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