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Article

Polymorphisms in Toll-like receptors 2, 4, and 9 are highly associated with hearing loss in survivors of bacterial meningitis.

PloS one - 1 Jan 2012

van Well Gijs Th J, Sanders Marieke S, Ouburg Sander, van Furth A Marceline, Morré Servaas A

Abstract excerpt

Genetic variation in innate immune response genes contributes to inter-individual differences in disease manifestation and degree of complications upon infection. We recently described an association of single nucleotide polymorphisms (SNPs) in TLR9 with susceptibility to meningococcal meningitis (MM). In this study, we investigate the association of SNPs in multiple pathogen recognition and immune response genes...

Read the complete abstract on PubMed

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Share to Hearing Loss
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Meningitis, Bacterial

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Share to Toll-Like Receptor 2

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Source

Open in PubMed Open full text

Identifiers

PMID: 22662111
DOI: 10.1371/journal.pone.0035837
PMCID: PMC3360733

Genes

TLR4
TLR9
TLR2
CASP1
NOD1
NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphisms in Toll-like receptors 2, 4, and 9 are highly associated with hearing loss in survivors of bacterial meningitis.PMID 22662111Read ↗

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