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Article

Analysis of TLR2, TLR4, and TLR9 single nucleotide polymorphisms in children with bacterial meningitis and their healthy family members.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Jul 2017

Gowin Ewelina, Świątek-Kościelna Bogna, Kałużna Ewelina, Nowak Jerzy, Michalak Michał, Wysocki Jacek, Januszkiewicz-Lewandowska Danuta

Abstract excerpt

BACKGROUND: The aim was to analyse TLR2 rs5743708, TLR2 rs4696480, TLR4 rs4986790, TLR9 rs5743836, and TLR9 rs352140 single nucleotide polymorphisms (SNPs) in children with pneumococcal and meningococcal meningitis and their family members. METHODS: The study group consisted of 39 children with bacterial meningitis (25 with meningococcal meningitis and 14 with pneumococcal meningitis) and 49 family members....

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Topics

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Cerebrospinal Fluid
Immunocompetence
Meningitis, Meningococcal
Neisseria meningitidis
Streptococcus pneumoniae
Toll-Like Receptor 2
Toll-Like Receptor 4
Toll-Like Receptor 9

Source

Identifiers

PMID: 28487240
DOI: 10.1016/j.ijid.2017.04.024

Genes

TLR9
TLR2
TLR4

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