Article
Differential epigenetic compatibility of qnr antibiotic resistance determinants with the chromosome of Escherichia coli.
PloS one - 1 Jan 2012
Sánchez María B, Martínez José L
Abstract excerpt
Environmental bacteria harbor a plethora of genes that, upon their horizontal transfer to new hosts, may confer resistance to antibiotics, although the number of such determinants actually acquired by pathogenic bacteria is very low. The founder effect, fitness costs and ecological connectivity all influence the chances of resistance transfer being successful. We examined the importance of these bottlenecks using...
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