Article
Crossveinless d is a vitellogenin-like lipoprotein that binds BMPs and HSPGs, and is required for normal BMP signaling in the Drosophila wing.
Development (Cambridge, England) - 1 Jun 2012
Chen Jun, Honeyager Shawn M, Schleede Justin, Avanesov Andrei, Laughon Allen, Blair Seth S
Abstract excerpt
The sensitivity of the posterior crossvein in the pupal wing of Drosophila to reductions in the levels and range of BMP signaling has been used to isolate and characterize novel regulators of this pathway. We show here that crossveinless d (cv-d) mutations, which disrupt BMP signaling during the development of the posterior crossvein, mutate a lipoprotein that is similar to the vitellogenins that comprise the...
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